When individuals are affected by histamine toxicity, the following foods cause the following issues
- Trigger mast cell degranulation causing allergic reactions systemically
- Cause gastrointestinal disturbances due to rich histamine content with body’s inability to break down histamine due to pancreatic insufficiency.
Histamine rich foods (cause gastrointestinal and skin reactions)
- Dairy. Mature cheeses (cheddar, stilton, roquefort, brie, parmesan and blue, camembert, romano, feta, colby, cheshire), kefir, buttermilk, margarine, flavored milks, soy milk, sour milk, goat cheese, whey protein, sour cream (only if not fresh or used in cooking).
- Eggs. Raw whites such as used in milk shakes, eggnog. Cooked plain eggs are sometimes ok.
- Fish. Mackerel, sardines, herring, shellfish, herring, trout, any canned, frozen, smoked or otherwise processed. Avoid fish unless it’s gutted and cooked within 1 hour.
- Meats. Processed or aged meats including sausage, hot dogs, salami, pepperoni, smoked meats, jerky, deli, and cured meats including bacon
- Vegetables. Tomatoes, eggplant, mushrooms, spinach, pumpkin, peas, relishes.
- Fruits (fresh). Banana, avocado, strawberries, aubergines, kiwi, pears, raspberries, papaya, orange, grapefruit, nectarine, dates, cranberry, cherry, loganberry, apricot.
- Fruits (dried). Apricots, prunes, dates, raisins, figs, plums, buckwheat, pineapples (delayed 24-72 hours histamine response)
- Vinegar. Any foods that might contain vinegar such as salad dressings, ketchup, mayonnaise, relishes, pickles. Use olive oil/lemon juice home made sauce instead. Balsamic vinegar (aged) is almost 10 richer in histamine than ACV.
- Sauces. Chilli, miso, soy, mustard and any others that may contain vinegar or garlic.
- Beverages. Alcohol, wine, champagne, cider, root beer, veer, ale, soft drinks, energy drinks, teas, juices from oranges, pineapples, peach, cranberries, nectarines.
- Fermented foods. Sauerkraut, smoked meats, pickled cucumbers, canned and fermented vegetables.
- Seasonings & spices. Curry power, cinnamon, cloves, anise, nutmeg, paprika.
- Deserts. Chocolate and cocoa powder containing deserts, gelatin, jams, jellies, candies and desert fillings
- Proteins. Any processed proteins.
- Frozen meals. Should be avoided completely as the preservatives and product aging are offensive.
- Any foods and especially meats that are older than 2 hours after cooking.
- Other. Honey, legumes, kidney beans, baking mixes, soy lecithin, low fat diets, hormones in milk,
- Supplements. Vitamin B12 (not methyl), folic acid (not methyl), glycine, histidine and fish oil trigger the release of histamine by mast cells. Additionally L-Tryptophan can cause an increased synthesis of metabolites such as indolyl and formate which significantly reduce breakdown of histamine via inhibition of DAO activity.
- Drugs. Some of the drugs may inhibit histamine breakdown enzyme activity. These include but not limited to NAC (N-acetyl cysteine), NSAIDs, Thiopental, Alprenolol, Cyclophosphamide, ambroxol, Bupropion, Paxil, Lexapro, Tranylcypromine, Celexa, Prozac, Zoloft, Effexor, Verapamil, dihydralazine, Metoclopramide, cefotiam, Cimetidine, Isoniazid, Propafenone, Amiloride, Morphine, cefuroxime.
Foods that trigger mast cells degranulation and an autoimmune response (expressed as chills and systemic toxicity)
- Grains. Gluten grains, corn (contains gluten called “zien”)
- Nuts and seeds. Trail mixes, most nuts and sees are high in tyramine content, breakfast cereals, granola bars, peanut butter, almonds, hazelnuts.
- Drinks. Alcohol, caffeine and hot foods
- Food additives. Nitrites, benzoate, dyes, glutamate, sulphites, vinegar, iodine, overripe fruits, curry, garlic.
- Other. Baker’s yeast, refined table salt (including iodized), hydrogenated oils, salicylates,
- Natural sulfates in aged meats and cheeses, eggs, grapes, bananas, garlic, corn starch, leeks, lettuce, maple syrup, onions, soy, tomatoes, chives, asparagus.
- Sulfate additives in apple cider, wines, beer, jams, gravies, mustard, horseradish, dried fruits, french fries, pickled vegetables and meats, processed foods, shrimp and shellfish.
- Skin care products. Should be avoid except for natural soaps, such as those made of olive oil.
- Oral care. Fluoride. Mouth washes can be replaced with a mixture of salt and baking soda. Tooth paste products should contain no fluoride or any other inorganic additives.
If you are affected by histamine rich foods and foods that trigger histamine release, you are most likely affected by pancreatic insufficiency.